Apparatus and associated methods relate to a clock generation circuit which generates asynchronous clock signals for a successive approximation ADC architecture based on time-interleaved comparators. In an illustrative example, a circuit may include (a) a first comparator configured to receive an input signal and generate a first ready signal to indicate a comparison decision being complete, (b) a second comparator configured to receive the input signal and generate a second ready signal to indicate a comparison decision being complete, and (c) a clock generation circuit coupled to receive the first and the second ready signals and generate a first clock for the first comparator and a second clock for the second comparator. The first and the second clock signals may be in anti-phase. Thus, each comparator may have enough time to reach a valid comparison in each successive approximation cycle, and kickback noises at comparator’ inputs may be advantageously reduced.